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In the news · Business Insider (via GLOBE NEWSWIRE) · Oct 05, 2026

Digbi Health Study of Nearly 16,000 Members Finds Precision Biology GI Care Delivers IBS Relief at Scale

Business Insider's markets site carried Digbi Health's release on a real-world study of nearly 16,000 members of its precision biology program, which tailors nutrition and lifestyle care to each person's gut microbiome, genetics and glucose response. After correcting for regression to the mean, the bias that flatters most single-arm digital health studies, members' IBS symptom scores fell by close to 48 points at 12 weeks, and more than half of symptomatic members crossed the 50-point threshold for clinically meaningful relief. The response grew with severity, and it held across age, sex, income and ethnicity subgroups and against medication use and the start of GLP-1 therapy. Improvement tracked the nutrient density of members' meals, not their weight change, which points to food quality matched to biology rather than weight loss as the lever for gut symptoms. For employers and health plans, the study puts real-world evidence behind GI care delivered inside a single program that also covers metabolic, inflammatory and hormonal conditions through one care team. The analysis is a preprint on medRxiv and has not yet been peer reviewed.

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